Anti-TROP2 antibodies, human

Anti-TROP2 antibodies, human

Clone: REA916 | Dilution: 1:50
Clone REA916 recognizes the human TROP2 antigen, a type I membrane glycoprotein also known as tumor-associated calcium signal transducer 2 (TACSTD2). TROP2 acts as a signal transducer and may be involved in regulating the growth of carcinoma cells. It is strongly expressed by a variety of human carcinomas, but also on trophoblasts and epithelial cells.
Additional information: Clone REA916 displays negligible binding to Fc receptors.

Alternative names

TACSTD2, GA733-1, M1S1, TROP2, EGP-1

Technical specifications

  • Antigen: TROP2
  • Clone: REA916
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TACSTD2, GA733-1, M1S1, TROP2, EGP-1
  • Entrez Gene ID: 4070
  • Molecular mass of antigen [kDa]: 33
  • Distribution of antigen: placenta, pancreatic carcinoma cells, epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Fornaro, M. et al. (1995) Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas. Int. J. Cancer 62(5): 610-618
    2. Ripani, E. et al. (1998) Human Trop-2 is a tumor-associated calcium signal transducer. Int. J. Cancer 76(5): 671-676
    3. Cubas, R. et al. (2010) Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway. Mol. Cancer 9(253)
Product options: 8
for 30
tests
(1)
EUR 75.00
for 100
tests
(1)
EUR 185.00
for 30
tests
(1)
EUR 90.00
for 100
tests
(1)
EUR 220.00
for 30
tests
(1)
EUR 90.00
for 100
tests
(1)
EUR 220.00
for 30
tests
(1)
EUR 75.00
for 100
tests
(1)
EUR 185.00

Related products

1 products available