Anti-TCR Vβ10 antibodies, mouse

Anti-TCR Vβ10 antibodies, mouse

Clone: REA651 | Dilution: 1:10
Clone REA651 recognizes the mouse V beta 10 T cell receptor (TCR Vβ10). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ10 is a variant of the TCR β chain and is expressed on T cells having the a haplotype, but not with the b and c haplotype of the TCRβ gene complex.
Additional information: Clone REA651 displays negligible binding to Fc receptors.

Alternative names

TCR Vb10, Gm17526

Technical specifications

  • Antigen: TCR Vβ10
  • Clone: REA651
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TCR Vb10, Gm17526
  • Entrez Gene ID: 100124670
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Brenden, N. et al. (1999) Differential MHC expression requirements for positive selection of separate TCR Vb families. Immunogenetics 49(1): 1-6
    2. Bour, H. et al. (1999)
      Dramatic influence of V beta gene polymorphism on an antigen-specific CD8
      +
      T cell response
      in vivo
      .
      J. Immunol. 162(8): 4647-4656
    3. Deepe, G. S. Jr et al. (2002)
      Discordance between T-cell receptor expression and effector function in mice infected with
      Histoplasma capsulatum
      .
      Infect. Immun. 70(3): 1648-1652
Product options: 8
9 µg in 300 µL (1)
EUR 23.00
30 µg in 1 mL (1)
EUR 65.00
9 µg in 300 µL (1)
EUR 32.00
30 µg in 1 mL (1)
EUR 65.00
9 µg in 300 µL (1)
EUR 41.00
30 µg in 1 mL (1)
EUR 85.00
9 µg in 300 µL (1)
EUR 12.00
30 µg in 1 mL (1)
EUR 35.00

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