Anti-Jagged2 antibodies, human

Anti-Jagged2 antibodies, human

Clone: REA1036 | Dilution: 1:50
Clone REA1036 recognizes the human Jagged2 protein, which is one of the several mammalian Notch ligands. Jagged2 is expressed by various organs and cell types and is involved in regulation of cell differentiation processes, such as lymphocyte development, myogenesis, and neurogenesis. Jagged2 is reported to be essential for the regulation of spermatogenesis. Jagged2 is also expressed on some lymphoma and leukemia cells and various other tumor cells and can be expressed by various antigen-presenting cells (APC) and may contribute to APC-directed peripheral T cell differentiation.
Additional information: Clone REA1036 displays negligible binding to Fc receptors

Alternative names

JAG2, HJ2, SER2

Technical specifications

  • Antigen: Jagged2
  • Clone: REA1036
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: JAG2, HJ2, SER2
  • Entrez Gene ID: 3714
  • Molecular mass of antigen [kDa]: 131
  • Distribution of antigen: tumor cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE-Vio615, PE-Vio770, APC-Vio770, Biotin, PE, APC
  • Selected references

    1. Luo, B. et al. (1997) Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor. Mol. Cell. Biol. 17(10): 6057-6067
    2. Passos, G. S. et al. (2006) Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects. Schizophr. Res. 88(1–3): 275-282
Product options: 12
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EUR 220.00
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EUR 100.00
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EUR 240.00
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EUR 100.00
for 100
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EUR 240.00
for 30
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EUR 100.00
for 100
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EUR 240.00
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EUR 75.00
for 100
tests
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EUR 185.00