Anti-Cytokeratin 8 antibodies, human

Anti-Cytokeratin 8 antibodies, human

Clone: REA885 | Dilution: 1:50
Clone REA885 recognizes the human type II keratin protein cytokeratin 8, an intermediate filament protein, which is found in epithelial and carcinoma cells. In adult tissues cytokeratin 8 is expressed as a heterodimer with cytokeratin 18.
Keratins play a critical role in mechanical stability and integrity of epithelial cells and tissues, have regulatory functions, and are involved in intracellular signaling pathways.
Additional information: Clone REA885 displays negligible binding to Fc receptors.

Alternative names

Cytokeratin-8, CK-8, Keratin-8

Technical specifications

  • Antigen: Cytokeratin 8
  • Clone: REA885
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: Cytokeratin-8, CK-8, Keratin-8
  • Entrez Gene ID: 3856
  • Molecular mass of antigen [kDa]: 54
  • Distribution of antigen: epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC
  • Selected references

    1. Leube, R. E. et al. (1986)
      Cytokeratin expression in simple epithelia. III. Detection of mRNAs encoding human cytokeratins nos. 8 and 18 in normal and tumor cells by hybridization with cDNA sequences
      in vitro
      and
      in situ
      .
      Differentiation 33(1): 69-85
    2. Krauss, S. et al. (1990) Organization and sequence of the human gene encoding cytokeratin 8. Gene 86(2): 241-249
    3. Moll, R. et al. (2008) The human keratins: biology and pathology. Histochem. Cell Biol. 129(6): 705-733
Product options: 6
for 30
tests
(1)
EUR 80.00
for 100
tests
(1)
EUR 190.00
for 30
tests
(1)
EUR 95.00
for 100
tests
(1)
EUR 225.00
for 30
tests
(1)
EUR 95.00
for 100
tests
(1)
EUR 225.00

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