Anti-Cytochrome c antibodies, human, mouse, rat

Anti-Cytochrome c antibodies, human, mouse, rat

Clone: REA702 | Dilution: 1:50
Clone REA702 recognizes the human, mouse, and rat cytochrome c, a 15 kDa hemeprotein located in the intermembrane of the mitochondrion. Cytochromes are involved in cell respiration, photosynthesis, and other biochemical reactions. Cytochrome c plays also a role in apoptosis, by release to cytoplasma and binding Apaf-1 which activates procaspase 9. Cytochrome c is found in plants, animals, and many unicellular organisms and catalyzes the electron transfer from reduced cytochrome c to oxygen.
Additional information: Clone REA702 displays negligible binding to Fc receptors.

Alternative names

Cyt c

Technical specifications

  • Antigen: Cytochrome c
  • Clone: REA702
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (I) antibodies
  • Alternative names of antigen: Cyt c
  • Entrez Gene ID: 54205, 13063, 25309
  • Molecular mass of antigen [kDa]: 12
  • Distribution of antigen: ubiquitous
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC
  • Selected references

    1. Margoliash, E. (1963) Primary structure and evolution of cytochrome c. Proc. Natl. Acad. Sci. U.S.A. 50: 672-679
    2. Ferguson, H. A. et al. (2003) UV-induced apoptosis is mediated independent of caspase-9 in MCF-7 cells: a model for cytochrome c resistance. J. Biol. Chem. 278(46): 45793-45800
    3. Tafani, M. et al. (2002) Cytochrome c release upon Fas receptor activation depends on translocation of full-length bid and the induction of the mitochondrial permeability transition. J. Biol. Chem. 277(12): 10073-10082
Product options: 6
for 30
tests
(1)
EUR 75.00
for 100
tests
(1)
EUR 185.00
for 30
tests
(1)
EUR 90.00
for 100
tests
(1)
EUR 220.00
for 30
tests
(1)
EUR 90.00
for 100
tests
(1)
EUR 220.00

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