Clone:
REA946
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
TCR Vb12

Specifications for TCR Vβ12 Antibody, anti-mouse, REAfinity™

Overview

Clone REA946 recognizes the mouse V beta 12 T cell receptor (TCR Vβ12). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules and plays an important role in T cell mediated immune responses. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. REA946 recognizes TCR Vβ12 on mouse strains with b haplotypes (e.g., BALB/c, C3H, and DBA/1).
Additional information: Clone REA946 displays negligible binding to Fc receptors.

Alternative names

TCR Vb12

Detailed product information

Technical specifications

CloneREA946
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenTCR Vβ12
Alternative names of antigenTCR Vb12
Distribution of antigenT cells
RRIDAB_2727138, AB_2727150, AB_2727139, AB_2727151, AB_2727140, AB_2727154, AB_2727142, AB_2727155, AB_2727143, AB_2727152, AB_2727141, AB_2727153, AB_2819378, AB_2727148, AB_2727137, AB_2727149

Resources for TCR Vβ12 Antibody, anti-mouse, REAfinity™

Certificates

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References for TCR Vβ12 Antibody, anti-mouse, REAfinity™

Publications

  1. Vacchio, M. S. and Hodes, R. J. (1989) Selective decreases in T cell receptor V beta expression. Decreased expression of specific V beta families is associated with expression of multiple MHC and non-MHC gene products. J. Exp. Med. 170(4): 1335-1346

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