Clone:
REA555
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC, MICS, IF, IHC
Alternative names:
FACT, FACT80, T160, FACTp80, hSSRP1

Specifications for SSRP1 Antibody, anti-human/mouse, REAfinity™

Overview

Clone REA555 recognizes the human and mouse SSRP1 antigen, which is a protein including a component of the FACT (facilitates chromatin transcription) complex. FACT acts subsequent to transcription initiation to release RNA polymerase II from a nucleosome-induced block to productive transcription. It is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication, and DNA repair.
Additional information: Clone REA555 displays negligible binding to Fc receptors.

Alternative names

FACT, FACT80, T160, FACTp80, hSSRP1

Detailed product information

Technical specifications

CloneREA555
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse
AntigenSSRP1
Alternative names of antigenFACT, FACT80, T160, FACTp80, hSSRP1
Molecular mass of antigen [kDa]81(same molecular weight for human and mouse/rat)
Distribution of antigenother
Entrez Gene ID6749, 20833
RRIDAB_2653550, AB_2653551, AB_2653552, AB_2653553

Resources for SSRP1 Antibody, anti-human/mouse, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for SSRP1 Antibody, anti-human/mouse, REAfinity™

Publications

  1. Belotserkovskaya, R. et al. (2003) FACT facilitates transcription-dependent nucleosome alteration. Science 301: 1090-1093
  2. LeRoy, G. et al. (1998)
    Requirement of RSF and FACT for transcription of chromatin templates
    in vitro
    .
    Science 282: 1900-1900
  3. Orphanides, G. et al. (1998) FACT, a factor that facilitates transcript elongation through nucleosomes. Cell 92(1): 105-116

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SSRP1 Antibody, anti-human/mouse, REAfinity™

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