Clone:
REA564
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
RT1-B, MHC-class II, MHC2, MHCII

Specifications for RT1B Antibody, anti-mouse/rat, REAfinity™

Overview

Clone REA564 recognizes non-polymorphic determinants of the mouse and rat RT1B antigen, also known as MHC class II antigen. MHC class II molecules are expressed in professional, immune antigen presenting cells, such as B lymphocytes, epidermal Langerhans cells, dendritic cells, some tissue macrophages, subsets of thymocytes, peritoneal mast cells, and small intestinal villus epithelium. REA564 recognizes the RT1B antigen expressed by C3H mice, but not by Balb/c or C57BL6 mice.
Additional information: Clone REA564 displays negligible binding to Fc receptors.

Alternative names

RT1-B, MHC-class II, MHC2, MHCII

Detailed product information

Technical specifications

CloneREA564
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse, rat
AntigenRT1B
Alternative names of antigenRT1-B, MHC-class II, MHC2, MHCII
Molecular mass of antigen [kDa]27
Distribution of antigenlymphocytes, Langerhans cells, dendritic cells, macrophages, mast cells, thymocytes
Entrez Gene ID24738, 309621
RRIDAB_2653371, AB_2653372, AB_2653373, AB_2653374, AB_2653375, AB_2653376, AB_2653377, AB_2653378, AB_2653379, AB_2653380, AB_2653381, AB_2653382, AB_2653383, AB_2653384, AB_2653385, AB_2653370

Resources for RT1B Antibody, anti-mouse/rat, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for RT1B Antibody, anti-mouse/rat, REAfinity™

Publications

  1. McMaster, W. R. et al. (1979) Identification of Ia glycoproteins in rat thymus and purification from rat spleen. Eur. J. Immunol. 9(6): 426-433
  2. Chen-Woan, M. et al. (1996)
    In vitro
    characterization of rat bone marrow-derived dendritic cells and their precursors.
    J. Leukoc. Biol. 59: 196-207
  3. Damoiseaux, J. G. et al. (1998) Costimulatory molecules CD80 and CD86 in the rat; tissue distribution and expression by antigen-presenting cells. J. Leukoc. Biol. 64(6): 803-809
  4. Wedekind, D. et al. (1997) Identification and differentiation of transcribed major histocompatibility complex class II RT1B alpha and RT1B beta alleles from laboratory rats. Transplant. Proc. 29(3): 1668-1669
  5. Male, D. K. et al. (1987) Serological evidence for a defect in RT1.B (I-A) expression by the BDIX rat strain. J. Immunogenet. 14(6): 301-312

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