Clone:
REAL453
Type of antibody:
Releasable antibodies, Primary antibodies, Recombinant antibodies
Applications:
FC
Alternative names:
Klra6, Lymphocyte antigen 49f, T-cell surface glycoprotein Ly-49F, Ly-49F

Specifications for Ly-49F Antibody, anti-mouse,
REAlease
®

Overview

Clone REAL453 is an antibody fragment derived from the full Ly-49F antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REA453 recognizes the mouse Ly-49F antigen (killer cell lectin-like receptor 6), a type II transmembrane natural killer (NK) cell receptor belonging to the Ly-49 family. Members of the Ly-49 family are homodimeric C-type lectin receptors, recognizing MHC class I molecules as ligands and include activating and inhibitory receptor molecules. The inhibitory receptor Ly-49F is expressed on subsets of NK cells, NK-T cells, and on a subpopulation of memory T cells in C57BL/6 mice, but not AKR/J, BALB/c, C3H/HeN, DBA/1, or SJL mice. IL-21 selectively down-regulates Ly-49F on mature NK cells.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

Klra6, Lymphocyte antigen 49f, T-cell surface glycoprotein Ly-49F, Ly-49F

Detailed product information

Technical specifications

CloneREAL453
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable antibodies, Primary antibodies, Recombinant antibodies
Speciesmouse
AntigenLy-49F
Alternative names of antigenKlra6, Lymphocyte antigen 49f, T-cell surface glycoprotein Ly-49F, Ly-49F
Distribution of antigenNK cells, T cells, NKT cells
RRIDAB_2802038, AB_2802039, AB_2811496