Clone:
REA1009
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC
Alternative names:
IL5, B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor, TRF

Specifications for IL-5 Antibody, anti-mouse, REAfinity™

Overview

Clone REA1009 recognizes the mouse interleukin-5 (IL-5), which is is predominantly secreted by CD4
+
T cells. It promotes growth and activation of eosinophils. Furthermore, it is involved in a range of allergic reactions and mediates immune reactions against parasites. IL-5 also acts on other cell types such as B cells.
Additional information: Clone REA1009 displays negligible binding to Fc receptors.

Alternative names

IL5, B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor, TRF

Detailed product information

Technical specifications

CloneREA1009
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse, human
Cross-reactivityhuman
AntigenIL-5
Alternative names of antigenIL5, B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor, TRF
Molecular mass of antigen [kDa]13
Distribution of antigenT cells, T helper cells
Entrez Gene ID16191
RRIDAB_2751342, AB_2751354, AB_2751343, AB_2751353

References for IL-5 Antibody, anti-mouse, REAfinity™

Publications

  1. Schwarze, J. et al. (1999) IL-5 and eosinophils are essential for the development of airway hyperresponsiveness following acute respiratory syncytial virus infection. J. Immunol. 162(5): 2997-3004
  2. Brunet, L. R. et al. (1999)
    Interleukin 5 (IL-5) is not required for expression of a Tʜ2 response or host resistance mechanisms during murine
    schistosomiasis mansoni
    but does play a role in development of IL-4-producing non-T, non-B cells.
    Infect. Immun. 67(6): 3014-3018

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