Clone:
REA665
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC, MICS
Alternative names:
Interleukin-2, T cell growth factor, TCGF, EDF, KHF, MAF-C I, TDF

Specifications for IL-2 Antibody, anti-mouse, REAfinity™

Overview

Clone REA665 recognizes the mouse interleukin-2 (IL-2) antigen. The T cell growth factor IL-2, mainly produced by activated CD4
+
T cells, is a central regulator of the immune response. It induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 has been found to stimulate growth and differentiation of B cells, NK cells, monocytes, and oligodendrocytes. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance, and anti-inflammatory reactions.
Additional information: Clone REA665 displays negligible binding to Fc receptors.

Alternative names

Interleukin-2, T cell growth factor, TCGF, EDF, KHF, MAF-C I, TDF

Detailed product information

Technical specifications

CloneREA665
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenIL-2
Alternative names of antigenInterleukin-2, T cell growth factor, TCGF, EDF, KHF, MAF-C I, TDF
Molecular mass of antigen [kDa]17
Distribution of antigenT cells
Entrez Gene ID16183
RRIDAB_2733293, AB_2752028, AB_2751995, AB_2733292

Resources for IL-2 Antibody, anti-mouse, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for IL-2 Antibody, anti-mouse, REAfinity™

Publications

  1. Matesanz, F. et al. (1992) A new cDNA sequence for the murine interleukin-2 gene. Biochim. Biophys. Acta 1132(3): 335-336
  2. Matesanz, F. et al. (1993) Existence of at least five interleukin-2 molecules in different mouse strains. Immunogenetics 38(4): 300-303
  3. Fuse, A. et al. (1984) Organization and structure of the mouse interleukin-2 gene. Nucleic Acids Res. 12(24): 9323-9331

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