ExiTron nano 6000 is an alkaline earth metal-based nanoparticulate contrast agent specifically formulated for preclinical computed tomography (CT).
It shows strong X-ray absorption due to the high metal load of theparticles.
Upon intravenous injection, ExiTron nano 6000 circulates in the blood stream and is taken up by the Kupffer cells (macrophages of the liver). It accumulates particularly in the liver and spleen and provides long-term X-ray contrast.

Data and images for ExiTron nano 6000

Figures

Figure 1

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Schematic diagram of an ExiTron nano 6000 nanoparticle.

Figure 1

Schematic diagram of an ExiTron nano 6000 nanoparticle.

Specifications for ExiTron nano 6000

Overview

ExiTron nano 6000 is an alkaline earth metal-based nanoparticulate contrast agent specifically formulated for preclinical computed tomography (CT).
It shows strong X-ray absorption due to the high metal load of theparticles.
Upon intravenous injection, ExiTron nano 6000 circulates in the blood stream and is taken up by the Kupffer cells (macrophages of the liver). It accumulates particularly in the liver and spleen and provides long-term X-ray contrast.

Detailed product information

Applications

ExiTron nano 6000 is indicated for use in CT of small animals, for example mice, to facilitate the visualization of the liver and spleen.
Examples include imaging of liver tumors and metastases.

References for ExiTron nano 6000

Publications

  1. Boll, H. et al. (2010) High-speed single-breath-hold micro-computed tomography of thoracic and abdominal structures in mice using a simplified method for intubation. J. Comput. Assist. Tomogr. 34: 783-790
  2. Boll, H. et al. (2011) Micro-CT based experimental liver imaging using a nanoparticulate contrast agent: a longitudinal study in mice. PLoS One 6: e25692

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