Clone:
16-10A1
Type of antibody:
Primary antibodies
Isotype:
hamster IgG2κ
Applications:
FC
Alternative names:
B7-1, Cd28l, Ly-53, Ly53, MIC17, TSA1, B7, BB1

Specifications for CD80 Antibody, anti-mouse

Overview

The monoclonal antibody 16-10A1 recognizes mouse CD80 also known as B7, B7-1 or Ly-53. The 55 kDa member of the Ig superfamily is expressed on activated B cells, macrophages and dendritic cells. The interaction of CD80 and CD152 (CTLA-4) or CD28 induces T cell proliferation and cytokine production.

Alternative names

B7-1, Cd28l, Ly-53, Ly53, MIC17, TSA1, B7, BB1

Detailed product information

Technical specifications

Clone16-10A1
Clonalitymonoclonal
Isotypehamster IgG2κ
Hosthamster
Type of antibodyPrimary antibodies
Speciesmouse, other
Cross-reactivitydog
AntigenCD80
Alternative names of antigenB7-1, Cd28l, Ly-53, Ly53, MIC17, TSA1, B7, BB1
Molecular mass of antigen [kDa]30
Distribution of antigenB cells, dendritic cells, macrophages, monocytes, Langerhans cells, T cells
Entrez Gene ID12519
RRIDAB_2659264, AB_2659265, AB_2659266, AB_2659267, AB_2659268, AB_2659269, AB_2659270, AB_2659271, AB_2659272, AB_2659273

Reviews for CD80 Antibody, anti-mouse

Staining CD80 in Skin

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CD80-PE, mouse (130-102-613)

It works well to detect targeted cells in the skin.

Staining CD80 in Skin

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CD80-PE, mouse (130-102-883)

It works well to detect targeted cells in the skin.

References for CD80 Antibody, anti-mouse

Publications

  1. Bluestone, J. A. et al. (1995) New perspectives of CD28-B7-mediated T cell costimulation. Immunity 2(6): 555-559
  2. Hathcock, K. S et al. (1994) Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function. J. Exp. Med. 180(2): 631-640
  3. Harlan, D. M. et al. (1994) Mice expressing both B7-1 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown of T-lymphocyte unresponsiveness. Proc. Natl. Acad. Sci. U.S.A. 91: 3137-3141
  4. Razi-Wolf, Z. et al. (1992) Expression and function of the murine B7 antigen, the major costimulatory molecule expressed by peritoneal exudate cells. Proc. Natl. Acad. Sci. U.S.A. 89: 4210 -4214

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