Clone:
REA1075
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
TP120, T12

Specifications for CD6 Antibody, anti-human, REAfinity™

Overview

Clone REA1075 recognizes the human CD6 antigen, a 100 kDa transmembrane glycoprotein. CD6 is expressed on the majority of T cells as well as on a subset of B cells in peripheral blood. The CD6 antigen is also expressed at low levels on immature thymocytes and at high levels on mature thymocytes. CD6 functions as an adhesion molecule as well as costimulatory molecule for TCR-mediated T cell activation.
Additional information: Clone REA1075 displays negligible binding to Fc receptors.

Alternative names

TP120, T12

Detailed product information

Technical specifications

CloneREA1075
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, non-human primate
Cross-reactivity
rhesus monkey (
Macaca mulatta
)
,
cynomolgus monkey (
Macaca fascicularis
)
AntigenCD6
Alternative names of antigenTP120, T12
Molecular mass of antigen [kDa]70
Distribution of antigenB cells, T cells, B cell subsets, thymocytes, CNS cells
Entrez Gene ID923
RRIDAB_2733650, AB_2733826, AB_2733827, AB_2733389, AB_2733390, AB_2733948, AB_2733949, AB_2732982, AB_2732983, AB_2733242, AB_2733243, AB_2733137, AB_2733138, AB_2733039, AB_2733040, AB_2734025, AB_2734026, AB_2733530, AB_2733531, AB_2733649

Resources for CD6 Antibody, anti-human, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD6 Antibody, anti-human, REAfinity™

Publications

  1. Bowen, M. A. et al. (1995) Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand. J. Exp. Med. 181: 2213-2220
  2. Hassan, N. J. et al. (2004) Frontline: Optimal T cell activation requires the engagement of CD6 and CD166. Eur. J. Immunol. 34(4): 930-940

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