Clone:
REA1183
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
Integrin alpha-5, VLA-5, ITGA5

Specifications for CD49e Antibody, anti-mouse, REAfinity™

Overview

Clone REA1183 recognizes mouse CD49e, also known as integrin α5, which interacts with integrin β1 (CD29) to form the heterodimer VLA-5, the fibronectin receptor. It is expressed on activated T cells, thymocytes, mast cells, and splenic B cells and plays a role in cell-surface mediated signaling and in adhesion.
Additional information: Clone REA1183 displays negligible binding to Fc receptors.

Alternative names

Integrin alpha-5, VLA-5, ITGA5

Detailed product information

Technical specifications

CloneREA1183
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD49e
Alternative names of antigenIntegrin alpha-5, VLA-5, ITGA5
Molecular mass of antigen [kDa]110
Distribution of antigenT cells, mast cells, B cells, thymocytes
Entrez Gene ID16402
RRIDAB_2784240, AB_2784243, AB_2784242, AB_2784241

Resources for CD49e Antibody, anti-mouse, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD49e Antibody, anti-mouse, REAfinity™

Publications

  1. Hemler, M. E. et al. (1990) LA proteins in the integrin family: structures, functions, and their role on leukocytes. Annu. Rev. Immunol. 8: 365-400
  2. Noto, K. et al. (1995) Identification and functional characterization of mouse CD29 with a mAb. Int. Immunol. 7: 835-842
  3. Rich, S. et al. (1996)
    Role of alpha 5 beta 1 integrin in TGF-beta 1-costimulated CD8
    +
    T cell growth and apoptosis.
    J. Immunol. 157: 2916-2923
  4. Yang, J. T. et al. (1996) Fibronectin receptor functions in embryonic cells deficient in alpha 5 beta 1 integrin can be replaced by alpha V integrins. Mol. Biol. Cell 7: 1737-1748

Related products for
CD49e Antibody, anti-mouse, REAfinity™

2 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?