Clone:
REA1225
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
CRTAM

Specifications for CD355 (CRTAM) Antibody, anti-human, REAfinity™

Overview

Clone REA1225 recognizes the human CD355 protein, a class I–restricted T cell–associated molecule (CRTAM). It is expressed on activated class I MHC restricted T cells, including CD8
+
T cells and NKT cells and binds nectin-like protein 2 (NecI2). The binding of CRTAM and NecI2 triggers cytotoxity of NK cells and IFN-γ secretion by CD8
+
T cells.
Additional information: Clone REA1225 displays negligible binding to Fc receptors.

Alternative names

CRTAM

Detailed product information

Technical specifications

CloneREA1225
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD355 (CRTAM)
Alternative names of antigenCRTAM
Molecular mass of antigen [kDa]43
Distribution of antigenT cells, NKT cells
Entrez Gene ID56253
RRIDAB_2819565, AB_2819571, AB_2819566, AB_2819572, AB_2819567, AB_2819573, AB_2819568, AB_2819574, AB_2819569, AB_2819570

References for CD355 (CRTAM) Antibody, anti-human, REAfinity™

Publications

  1. Boles, K. S. et al. (2005)
    The tumor suppressor TSLC1/NECL-2 triggers NK-cell and CD8
    +
    T-cell responses through the cell-surface receptor CRTAM.
    Blood 106: 779-786

Seems like you are coming from USA!
Do you want to visit our website in your country?