Clone:
REA890
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
FcRL4, FCRH4, IFGP2, IRTA1

Specifications for CD307d (FcRL4) Antibody, anti-human, REAfinity™

Overview

Clone REA890 recognizes the human CD307d antigen, a single-pass type I transmembrane protein also known as Fc receptor homolog 4 (FcRL4) or IRTA1. CD307d belongs to the Fc receptor homologue family, which members contain three potential immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their intracellular domain. CD307d is abundantly expressed on memory B cells and is able to inhibit the B cell receptor (BCR) signaling.
Additional information: Clone REA890 displays negligible binding to Fc receptors.

Alternative names

FcRL4, FCRH4, IFGP2, IRTA1

Detailed product information

Technical specifications

CloneREA890
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD307d (FcRL4)
Alternative names of antigenFcRL4, FCRH4, IFGP2, IRTA1
Molecular mass of antigen [kDa]55
Distribution of antigenB cells
Entrez Gene ID83417
RRIDAB_2726784, AB_2726705, AB_2726785, AB_2726706, AB_2726786, AB_2726707, AB_2726783, AB_2726704

Resources for CD307d (FcRL4) Antibody, anti-human, REAfinity™

Certificates

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References for CD307d (FcRL4) Antibody, anti-human, REAfinity™

Publications

  1. Miller, I. et al. (2002) IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells. Blood 99(8): 2662-2669
  2. Ehrhardt, G. R. et al. (2003) The inhibitory potential of Fc receptor homolog 4 on memory B cells. Proc. Natl. Acad. Sci. U.S.A. 100(23): 13489-13494
  3. Ehrhardt, G. R. et al. (2005) Expression of the immunoregulatory molecule FcRH4 defines a distinctive tissue-based population of memory B cells. J. Exp. Med. 202(6): 783-791

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