Clone:
MTS510 
Type of antibody:
Primary antibodies
Isotype:
rat IgG2aκ
Applications:
FC
Alternative names:
TLR4, Lps, Ly87, Ran/M1, Rasl2-8

Specifications for CD284 Antibody, anti-mouse

Overview

Clone MTS510 reacts with the molecular complex of CD284, a type I transmembrane signaling receptor, also known as toll-like receptor 4 (TLR4), associated with myeloid differentiation factor-2 (MD2). Toll-like receptors are a family of pattern recognition receptors detecting the presence and characteristics of an infection and induce appropriately tailored innate and adaptive immune responses. TLR4 associates with its coreceptor MD2. The resulting molecular complex is responsible for recognition and signaling upon specific lipopolysaccharide (LPS) binding. TLR4 is expressed on monocytes/macrophages as well as on myeloid dendritic cells. MTS510 detects TLR4 associated with MD2 on the surface of thioglycollate-elicited peritoneal macrophages from different mouse strains, for example, C57BL/6 or BALB/c.

Alternative names

TLR4, Lps, Ly87, Ran/M1, Rasl2-8

Detailed product information

Technical specifications

CloneMTS510 
Clonalitymonoclonal
Isotyperat IgG2aκ
Isotype controlIsotype Control Antibody, rat IgG2a
Hostrat
Type of antibodyPrimary antibodies
Speciesmouse
AntigenCD284
Alternative names of antigenTLR4, Lps, Ly87, Ran/M1, Rasl2-8
Molecular mass of antigen [kDa]93
Distribution of antigendendritic cells, endothelial cells, granulocytes, macrophages, monocytes, T cells, leukocytes, lymphocytes, placenta, spleen
Entrez Gene ID21898
RRIDAB_2660389, AB_2660390, AB_2660388

Resources for CD284 Antibody, anti-mouse

Certificates

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CD284 Antibody, anti-mouse

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