Clone:
R1.302
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC
Alternative names:
PVRL1, CLPED1, ED4, HV1S, HveC, OFC7, PRR, PVRR, Nectin-1

Specifications for CD111 Antibody, anti-human

Overview

Clone R1.302 recognizes the CD111 antigen, a 75 kDa type I transmembrane glycoprotein also known as poliovirus receptor related 1 protein (PRR1), PVRL1, HveC, and Nectin-1. Nectins are involved in the formation of the mechanical adhesive puncta adherentia junctions of synapses. CD111 is an adhesion molecule that can be found in a wide range of tissues where it localizes in various junctions such as the adherens junction of epithelial tissue or the chemical synapse of neurons. In the chemical synapse, CD111 interacts with PVRL3 and both proteins can be found in neuronal tissue already in early stages of brain development as well as in aging brains. CD111 also functions as an entry receptor for herpes simplex virus and pseudorabies virus.

Alternative names

PVRL1, CLPED1, ED4, HV1S, HveC, OFC7, PRR, PVRR, Nectin-1

Detailed product information

Technical specifications

CloneR1.302
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD111
Alternative names of antigenPVRL1, CLPED1, ED4, HV1S, HveC, OFC7, PRR, PVRR, Nectin-1
Molecular mass of antigen [kDa]54
Distribution of antigenother
Entrez Gene ID5818
RRIDAB_2654534, AB_2654535, AB_2654536, AB_2654537, AB_2654538, AB_2654539, AB_2654540, AB_2654541, AB_2654542, AB_2654533

Resources for CD111 Antibody, anti-human

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD111 Antibody, anti-human

Publications

  1. Cocchi, F. et al. (1998) The V domain of herpesvirus Ig-like receptor (HIgR) contains a major functional region in herpes simplex virus-1 entry into cells and interacts physically with the viral glycoprotein D. Proc. Natl. Acad. Sci. U.S.A. 95(26): 15700-15705
  2. Rikitake, Y. et al. (2012) The role of nectins in different types of cell-cell adhesion. J. Cell. Sci. 125: 3713-3722
  3. Takahashi, K. et al. (1999) Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein. J. Cell Biol. 145(3): 539-549

Related products for
CD111 Antibody, anti-human

3 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?