Clone:
REA658
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
Carbonic anhydrase IX, CA9, CAIX, CA-IX, MN

Specifications for Carbonic Anhydrase 9 Antibody, anti-human, REAfinity™

Overview

Clone REA658 recognizes the human carbonic anhydrase IX, a single-pass type I integral membrane protein detected in HeLa cells and in different human carcinomas. This tumor-associated isoenzyme is also expressed on the surface microvilli and in the nucleus. Carbonic anhydrase IX, also known as CAIX, CA9, or MN, is a member of the alpha-carbonic anhydrase family that catalyze the reversible hydration of carbon dioxide. It may plays a role in the control of cell proliferation and transformation and seems to be a novel specific biomarker for identifying cervical dysplasia and carcinoma. Carbonic anhydrases participate in a variety of biological processes.
Additional information: Clone REA658 displays negligible binding to Fc receptors.

Alternative names

Carbonic anhydrase IX, CA9, CAIX, CA-IX, MN

Detailed product information

Technical specifications

CloneREA658
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCarbonic Anhydrase 9
Alternative names of antigenCarbonic anhydrase IX, CA9, CAIX, CA-IX, MN
Molecular mass of antigen [kDa]46
Distribution of antigentumor cells, cancer stem cells
Entrez Gene ID768
RRIDAB_2857582, AB_2651326, AB_2651327, AB_2651328, AB_2651329, AB_2857585

Resources for Carbonic Anhydrase 9 Antibody, anti-human, REAfinity™

Certificates

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References for Carbonic Anhydrase 9 Antibody, anti-human, REAfinity™

Publications

  1. Pastorek, J. et al. (1994) Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene 9(10): 2877-2888
  2. Opavsky, R. et al. (1996) Human MN/CA9 gene, a novel member of the carbonic anhydrase family: structure and exon to protein domain relationships. Genomics 33(3): 480-487

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