CD50 (ICAM-3) antibodies, human

CD50 (ICAM-3) antibodies, human

Clone: REA905 | Dilution: 1:50
Clone REA905 recognizes the human CD50 antigen, a type I transmembrane glycoprotein also known as intercellular adhesion molecule 3 (ICAM-3). As a member of the immunoglobulin superfamily, CD50 is closely related to ICAM-1 and consists of five immunoglobulin domains. It is expressed by leukocytes and is a ligand for CD11a (leukocyte adhesion LFA-1 protein). CD50 is also associated with the amino-terminal domain of ERM proteins and moesin and plays an essential role in primary immune responses.
Additional information: Clone REA905 displays negligible binding to Fc receptors.

Alternative names

Intercellular adhesion molecule 3, CDw50, ICAM-R, ICAM3

Technical specifications

  • Antigen: CD50 (ICAM-3)
  • Clone: REA905
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Intercellular adhesion molecule 3, CDw50, ICAM-R, ICAM3
  • Entrez Gene ID: 3385
  • Molecular mass of antigen [kDa]: 56
  • Distribution of antigen: leukocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, VioBlue, VioGreen, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin, FITC, PE
  • Selected references

    1. de Fougerolles, A. R. et al. (1992) Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes. J. Exp. Med. 175(1): 185-190
    2. Serrador, J. M. et al. (2002) A novel serine-rich motif in the intercellular adhesion molecule 3 is critical for its ezrin/radixin/moesin-directed subcellular targeting. J. Biol. Chem. 277(12): 10400-10409
Product options: 18
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GBP 180.00
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GBP 75.00
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GBP 190.00
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GBP 75.00
for 100
tests
(1)
GBP 190.00
for 30
tests
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GBP 80.00
for 100
tests
(1)
GBP 195.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 195.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 195.00
for 30
tests
(1)
GBP 60.00
for 100
tests
(1)
GBP 155.00

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