CD45RA antibodies, human

CD45RA antibodies, human

Clone: REA1047 | Dilution: 1:50
Clone REA1047 recognizes the human CD45RA antigen which is expressed on naive CD4
+
and CD8
+
T cells as well as on CD8
+
effector T cells. CD45RA is also present on subsets of B and NK cells as well as on plasmacytoid dendritic cells. The CD45RA antibody recognizes the 220 kDa isoform of the leukocyte common antigen (LCA), a transmembrane tyrosine phosphatase.
Additional information: Clone REA1047 displays negligible binding to Fc receptors.

Alternative names

Ptprc, B220, CD45, CD45R, GP180, L-CA, Ly-5, T200

Technical specifications

  • Antigen: CD45RA
  • Clone: REA1047
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Ptprc, B220, CD45, CD45R, GP180, L-CA, Ly-5, T200
  • Entrez Gene ID: 5788
  • Molecular mass of antigen [kDa]: 145
  • Cross-reactivity:
    chimpanzee (
    Pan troglodytes
    )
  • Distribution of antigen: B cells, monocytes, NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected references

    1. Cantisan, S. et al. (2010)
      CD45RA expression on HCMV-specific effector memory CD8
      +
      T cells is associated with the duration and intensity of HCMV replication after transplantation.
      Clin. Immunol. 137(1): 81-88
    2. Braun, T. et al. (2012)
      Effector CD4
      +
      CD45RA
      CD25
      bright
      Foxp3
      bright
      regulatory T cell (eTreg) distribution is significantly impaired in chronic myelomonocytic leukemia (CMML) and correlates with TET 2 mutational status.
      Blood 120: 2808-2808
Product options: 22
for 30
tests
(1)
GBP 50.00
for 100
tests
(1)
GBP 115.00
130-117-852

CD45RA-PE, human

for 30
tests
(1)
GBP 65.00
130-117-741

CD45RA-PE, human

for 100
tests
(1)
GBP 155.00
for 30
tests
(1)
GBP 65.00
for 100
tests
(1)
GBP 155.00
for 30
tests
(1)
GBP 75.00
for 100
tests
(1)
GBP 185.00
for 30
tests
(1)
GBP 75.00
for 100
tests
(1)
GBP 185.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 190.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 190.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 190.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 190.00
for 30
tests
(1)
GBP 100.00
for 100
tests
(1)
GBP 240.00
for 30
tests
(1)
GBP 50.00
for 100
tests
(1)
GBP 115.00

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