CD31 antibodies, human

CD31 antibodies, human

Clone: REA730 | Dilution: 1:50
Clone REA730 recognizes the human CD31 antigen, also known as PECAM-1. CD31 is a member of the immunoglobulin superfamily and is involved in leukocyte transmigration, angiogenesis, and integrin activation. CD31 is a 120–140 kDa single-chain transmembrane glycoprotein expressed on endothelial cells, monocytes, platelets, granulocytes, and several lymphocyte subsets. During maturation of CD4
+
T cells, the expression of CD31 changes: CD4
+
recent thymic emigrants (RTEs) express CD31 in contrast to central naive T cells. CD31 is highly expressed on endothelial cells, especially at their juncture.
Additional information: Clone REA730 displays negligible binding to Fc receptors.

Alternative names

PECAM-1, EndoCAM, GPIIa, PECA1

Technical specifications

  • Antigen: CD31
  • Clone: REA730
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: PECAM-1, EndoCAM, GPIIa, PECA1
  • Entrez Gene ID: 5175
  • Molecular mass of antigen [kDa]: 80
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Newman, P. J. et al. (1990) PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science 247(4947): 1219-1222
    2. Stockinger, H. et al. (1990) Molecular characterization and functional analysis of the leukocyte surface protein CD31. J. Immunol. 145(11): 3889-3897
    3. Kimmig, S. et al. (2002) Two subsets of naive T helper cells with distinct T cell receptor excision circle content in human adult peripheral blood. J. Exp. Med. 195: 789-794
Product options: 18
130-110-806

CD31-FITC, human

for 30
tests
(1)
GBP 60.00
130-110-668

CD31-FITC, human

for 100
tests
(1)
GBP 150.00
130-110-807

CD31-PE, human

for 30
tests
(1)
GBP 70.00
130-110-669

CD31-PE, human

for 100
tests
(1)
GBP 175.00
130-110-808

CD31-APC, human

for 30
tests
(1)
GBP 70.00
130-110-670

CD31-APC, human

for 100
tests
(1)
GBP 175.00
for 30
tests
(1)
GBP 75.00
for 100
tests
(1)
GBP 185.00
for 30
tests
(1)
GBP 75.00
for 100
tests
(1)
GBP 185.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 190.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 190.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 190.00
for 30
tests
(1)
GBP 60.00
for 100
tests
(1)
GBP 150.00

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