CD21/CD35 antibodies, mouse

CD21/CD35 antibodies, mouse

Clone: REA800 | Dilution: 1:50
Clone REA800 recognizes an epitope shared by mouse CD21 and CD35, also known as CR2 and CR1. CD21 and CD35 are alternatively spliced transcripts from the Cr2 gene, which produce cell-surface proteins of 145 and 190 kDa, respectively. CD21 and CD35 are expressed on the majority of peripheral B lymphocytes, on the majority of resident peritoneal macrophages, on mast cells, activated granulocytes, and follicular dendritic cells. CD21 forms part of a signal transduction complex with CD19 and CD81, which are associated with the antigen receptor on B lymphocytes.
Additional information: Clone REA800 displays negligible binding to Fc receptors.

Alternative names

CR2, C3dR, C3b/C4b-R, CR1, EBV-R, Immune adherence receptor

Technical specifications

  • Antigen: CD21/CD35
  • Clone: REA800
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: CR2, C3dR, C3b/C4b-R, CR1, EBV-R, Immune adherence receptor
  • Entrez Gene ID: 12902
  • Molecular mass of antigen [kDa]: 112
  • Distribution of antigen: B cells, basophils, dendritic cells, eosinophils, granulocytes, lymphocytes, macrophages, monocytes, neutrophils, NK cells, platelets, red blood cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected references

    1. Kozono, Y. et al. (1998) Cross-linking CD21/CD35 or CD19 increases both B7-1 and B7-2 expression on murine splenic B cells. J. Immunol. 160(4): 1565-1572
    2. Brockman, M. A. et al. (2006) Optimal long-term humoral responses to replication-defective herpes simplex virus require CD21/CD35 complement receptor expression on stromal cells. J. Virol. 80(14): 7111-7117
    3. Roozendaal, R. et al. (2007) Complement receptors CD21 and CD35 in humoral immunity. Immunol. Rev. 219: 157-166
Product options: 18
30 µg in 200 µL (1)
GBP 30.00
150 µg in 1 mL (1)
GBP 80.00
30 µg in 200 µL (1)
GBP 50.00
150 µg in 1 mL (1)
GBP 150.00
30 µg in 200 µL (1)
GBP 50.00
150 µg in 1 mL (1)
GBP 150.00
30 µg in 200 µL (1)
GBP 65.00
150 µg in 1 mL (1)
GBP 185.00
30 µg in 200 µL (1)
GBP 70.00
150 µg in 1 mL (1)
GBP 195.00
30 µg in 200 µL (1)
GBP 70.00
150 µg in 1 mL (1)
GBP 195.00
30 µg in 200 µL (1)
GBP 70.00
150 µg in 1 mL (1)
GBP 195.00
30 µg in 200 µL (1)
GBP 95.00
150 µg in 1 mL (1)
GBP 280.00
30 µg in 200 µL (1)
GBP 30.00
150 µg in 1 mL (1)
GBP 80.00

Related products

2 products available