CD20 antibodies, human

Clone: REA780 | Dilution: 1:50
Clone REA780 recognizes the CD20 antigen, a non-glycosylated transmembrane protein of 33–37 kDa that is expressed on B lineage cells from the pre–B cell stage to the B cell lymphoblast stage. The antigen is further expressed on most malignant B cells. CD20 is not found on early B cell progenitors or plasma cells. Oligomers of CD20 form a Ca
2+
channel and might function in the regulation of local responses during B cell activation.
Additional information: Clone REA780 displays negligible binding to Fc receptors.

Alternative names

MS4A1, B1, Bp35, CVID5, LEU-16, MS4A2, S7, Ly-44

Technical specifications

  • Antigen: CD20
  • Clone: REA780
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: MS4A1, B1, Bp35, CVID5, LEU-16, MS4A2, S7, Ly-44
  • Entrez Gene ID: 931
  • Molecular mass of antigen [kDa]: 33
  • Cross-reactivity:
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    rhesus monkey (
    Macaca mulatta
    )
  • Distribution of antigen: B cells, cancer stem cells, dendritic cells, lymphocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected references

    1. Countouriotis, T. B. et al. (2002) Cell surface antigen and molecular targeting in the treatment of hematologic malignancies. Stem Cells 20(3): 215-229
    2. Polyak et al. (2002) CD20 Workshop Panel report. In: Leucocyte typing VII, Oxford University Press.
    3. Lamprecht, B. et al. (2008) Aberrant expression of the Tʜ2 cytokine IL-21 in Hodgkin lymphoma cells regulates STAT3 signaling and attracts Treg cells via regulation of MIP-3alpha. Blood 112(8): 3339-3347
    4. Maxwell, S. A. et al. (2009) 14-3-3zeta J. Biol. Chem. 284(33): 22379-22389
Product options: 20
130-111-523

CD20-FITC, human

for 30
tests
(1)
GBP 60.00
130-111-337

CD20-FITC, human

for 100
tests
(1)
GBP 155.00
130-111-524

CD20-PE, human

for 30
tests
(1)
GBP 70.00
130-111-338

CD20-PE, human

for 100
tests
(1)
GBP 180.00
130-111-525

CD20-APC, human

for 30
tests
(1)
GBP 70.00
130-111-339

CD20-APC, human

for 100
tests
(1)
GBP 180.00
for 30
tests
(1)
GBP 75.00
for 100
tests
(1)
GBP 190.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 195.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 195.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 195.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 195.00
for 30
tests
(1)
GBP 105.00
for 100
tests
(1)
GBP 245.00
for 30
tests
(1)
GBP 60.00
for 100
tests
(1)
GBP 155.00

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