CD158a/h (KIR2DL1/DS1) antibodies, human

CD158a/h (KIR2DL1/DS1) antibodies, human

Clone: REA1010 | Dilution: 1:50
Clone REA1010 recognizes the human CD158a (KIR2DL1) and CD158h (KIR2DS1) antigens, two members of the killer immunoglobulin-like receptor (KIR) family expressed on CD56
dim
CD16
+
natural killer (NK) cells and CD8
+
T cells. CD158a (KIR2DL1) is involved in the transduction of an inhibitory signal whereas CD158h (KIR2DS1) is an activating receptor. The ligands of CD158a (KIR2DL1) are HLA-Cw4 and related molecules.
Additional information: Clone REA1010 displays negligible binding to Fc receptors.

Alternative names

KIR2DL1, KIR-K64, KIR221, NKAT, NKAT-1, p58.1, KIR2DS1

Technical specifications

  • Antigen: CD158a/h (KIR2DL1/DS1)
  • Clone: REA1010
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: KIR2DL1, KIR-K64, KIR221, NKAT, NKAT-1, p58.1, KIR2DS1
  • Entrez Gene ID: 3802
  • Molecular mass of antigen [kDa]: 36
  • Distribution of antigen: NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio615, PE-Vio770, APC-Vio770, VioBright 515
  • Selected references

    1. Falco, M. et al. (2010) Combined genotypic and phenotypic killer cell Ig-like receptor analyses reveal KIR2DL3 alleles displaying unexpected monoclonal antibody reactivity: identification of the amino acid residues critical for staining. J. Immunol. 185: 433-441
  • Customer reports and application notes

Product options: 10
for 30
tests
(1)
GBP 75.00
for 100
tests
(1)
GBP 185.00
for 30
tests
(1)
GBP 75.00
for 100
tests
(1)
GBP 185.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 195.00
for 100
tests
(1)
GBP 195.00
for 100
tests
(1)
GBP 195.00
for 30
tests
(1)
GBP 105.00
for 100
tests
(1)
GBP 245.00

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