CD153 antibodies, mouse

CD153 antibodies, mouse

Clone: RM153 | Dilution: 1:10
The monoclonal antibody RM153 reacts with mouse CD153 (CD30 ligand), a 40 kDa type II membrane protein belonging to the NGF/TNF superfamily. It is expressed by activated CD4
+
and CD8
+
T cells. The interaction between CD30 and CD153 enhance the proliferation of stimulated T cells. In the presence of the RM153 antibody this effect is blocked.
In vivo
treatment with this antibody is reported to inhibit or delay immune reactions.

Alternative names

TNFSF8, CD30LG, CD30L

Technical specifications

  • Antigen: CD153
  • Clone: RM153
  • Isotype: rat IgG2bκ
  • Isotype control: Rat IgG2b – isotype control antibodies
  • Alternative names of antigen: TNFSF8, CD30LG, CD30L
  • Entrez Gene ID: 21949
  • Molecular mass of antigen [kDa]: 27
  • Distribution of antigen: B cells, bone marrow, eosinophils, granulocytes, macrophages, monocytes, myeloid cells, neutrophils
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, Biotin, PE
  • Selected references

    1. al-Shamkhani, A. et al. (1996) OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand. Eur. J. Immunol. 26(8): 1695-1699
    2. Kjaergaard, J. et al. (2001) Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor. J. Immunol. 167: 6669-6677
    3. Akiba, H. et al. (1999) CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. J. Immunol. 162(12): 7058-7066
Product options: 3
130-102-575

CD153-PE, mouse

30 µg in 1 mL (1)
GBP 50.00
130-102-522

CD153-APC, mouse

30 µg in 1 mL (1)
GBP 50.00
30 µg in 1 mL (1)
GBP 30.00

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