CD10 antibodies, human

CD10 antibodies, human

Clone: REA877 | Dilution: 1:50
Clone REA877 recognizes the human CD10 antigen, also known as the common acute lymphoblastic leukemia antigen (CALLA). CD10 is a 100 kDa cell surface molecule identical to human membrane-associated neutral endopeptidase (NEP) and also known as neprilysin or enkephalinase.
Human CD10 is expressed on a wide variety of normal and neoplastic cell types from different tissues including neural and hematopoietic cells. It is expressed on pre– and pro–B cells and is involved in B cell development and differentiation. The antigen is also present on mature neutrophils, T cell precursors, and some T cell leukemias/lymphomas. Furthermore, CD10 is expressed on neoplastic cells of several B lymphoid leukemias/lymphomas.
Additional information: Clone REA877 displays negligible binding to Fc receptors.

Alternative names

MME, CALLA, NEP, SFE, gp100, Neprilysin, Enkephalinase

Technical specifications

  • Antigen: CD10
  • Clone: REA877
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: MME, CALLA, NEP, SFE, gp100, Neprilysin, Enkephalinase
  • Entrez Gene ID: 4311
  • Molecular mass of antigen [kDa]: 85
  • Distribution of antigen: B cells, bone marrow, brain, epithelial cells, fibroblasts, granulocytes, gut, kidney, leukemia cells, ES and iPS cells, smooth muscle, stromal cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Shipp, M. A. and Look, A. T. (1993) Hematopoietic differentiation antigens that are membrane-associated enzymes: cutting is the key! Blood 82: 1052-1070
    2. Kalled, S. L. et al. (1995) The distribution of CD10 (NEP 24.11, CALLA) in human and mice is similar in non-lymphoid organs but differ within the hematopoietic system: absence on murine T and B lymphoid progenitors. Eur. J. Immunol. 25: 677-687
Product options: 18
130-114-692

CD10-FITC, human

for 30
tests
(1)
GBP 60.00
130-114-501

CD10-FITC, human

for 100
tests
(1)
GBP 150.00
130-114-693

CD10-PE, human

for 30
tests
(1)
GBP 70.00
130-114-502

CD10-PE, human

for 100
tests
(1)
GBP 175.00
130-114-694

CD10-APC, human

for 30
tests
(1)
GBP 70.00
130-114-503

CD10-APC, human

for 100
tests
(1)
GBP 175.00
for 30
tests
(1)
GBP 75.00
for 100
tests
(1)
GBP 185.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 190.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 190.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 190.00
for 30
tests
(1)
GBP 80.00
for 100
tests
(1)
GBP 190.00
for 30
tests
(1)
GBP 60.00
for 100
tests
(1)
GBP 150.00

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