Anti-TCR Vβ12 antibodies, mouse

Anti-TCR Vβ12 antibodies, mouse

Clone: REA946 | Dilution: 1:50
Clone REA946 recognizes the mouse V beta 12 T cell receptor (TCR Vβ12). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules and plays an important role in T cell mediated immune responses. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. REA946 recognizes TCR Vβ12 on mouse strains with b haplotypes (e.g., BALB/c, C3H, and DBA/1).
Additional information: Clone REA946 displays negligible binding to Fc receptors.

Alternative names

TCR Vb12

Technical specifications

  • Antigen: TCR Vβ12
  • Clone: REA946
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TCR Vb12
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, VioBright 515, Biotin
  • Selected references

    1. Vacchio, M. S. and Hodes, R. J. (1989) Selective decreases in T cell receptor V beta expression. Decreased expression of specific V beta families is associated with expression of multiple MHC and non-MHC gene products. J. Exp. Med. 170(4): 1335-1346
Product options: 16
30 µg in 200 µL (1)
GBP 30.00
150 µg in 1 mL (1)
GBP 80.00
30 µg in 200 µL (1)
GBP 50.00
150 µg in 1 mL (1)
GBP 150.00
30 µg in 200 µL (1)
GBP 50.00
150 µg in 1 mL (1)
GBP 150.00
30 µg in 200 µL (1)
GBP 65.00
150 µg in 1 mL (1)
GBP 185.00
30 µg in 200 µL (1)
GBP 70.00
150 µg in 1 mL (1)
GBP 195.00
30 µg in 200 µL (1)
GBP 70.00
150 µg in 1 mL (1)
GBP 195.00
30 µg in 200 µL (1)
GBP 70.00
30 µg in 200 µL (1)
GBP 95.00
30 µg in 200 µL (1)
GBP 30.00
150 µg in 1 mL (1)
GBP 80.00

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