Anti-Melanoma (MCSP) antibodies, human

Anti-Melanoma (MCSP) antibodies, human

Clone: EP-1 | Dilution: 1:11
The Anti-Melanoma (MCSP) antibody recognizes the melanoma-associated chondroitin sulfate proteoglycan (MCSP) antigen, also known as high molecular weight melanoma-associated antigen. MCSP is expressed on the majority (>90%) of human melanoma tissues and melanoma cell lines but not on carcinoma cells, fibroblastoid cells, and cells of hematopoietic origin.

Alternative names

CSPG4, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2

Technical specifications

  • Antigen: Melanoma (MCSP)
  • Clone: EP-1
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: CSPG4, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2
  • Entrez Gene ID: 1464
  • Molecular mass of antigen [kDa]: 248
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, VioBlue, Biotin
  • Selected references

    1. Benez, A. et al. (1999) Detection of circulating melanoma cells by immunomagnetic cell sorting. J. Clin. Lab. Anal. 13: 229-233
    2. Siewert, C. et al. (2001) Rapid enrichment and detection of melanoma cells from peripheral blood mononuclear cells by a new assay combining immunomagnetic cell sorting and immunocytochemical staining. Recent Results Cancer Res. 158: 51-60
    3. Morgan, A. C. et al. (1981) Production and characterization of monoclonal antibody to a melanoma specific glycoprotein. Hybridoma 1: 27-36
    4. Bumol, T. F. and Reisfeld, R. A. (1982) Unique glycoprotein-proteoglycan complex defined by monoclonal antibody on human melanoma cells. Proc. Natl. Acad. Sci. U.S.A. 79(4): 1245-1249
    5. Bumol, T. F. et al. (1984) Biosynthetic studies of proteoglycans in human melanoma cells with a monoclonal antibody to a core glycoprotein of chondroitin sulfate proteoglycans. J. Biol. Chem. 259(20): 12733-12741
    6. Pluschke, G. et al. (1996) Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan. Proc. Natl. Acad. Sci. U.S.A. 93(18): 9710-9715
  • Brochures and posters

Product options: 8
for 30
tests
(1)
GBP 60.00
for 100
tests
(1)
GBP 150.00
for 30
tests
(1)
GBP 70.00
for 100
tests
(1)
GBP 175.00
for 30
tests
(1)
GBP 75.00
for 100
tests
(1)
GBP 185.00
for 30
tests
(1)
GBP 60.00
for 100
tests
(1)
GBP 150.00

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