Anti-FcεRIα antibodies, human

Anti-FcεRIα antibodies, human

Clone: REA758
Clone REA758 recognizes the human FcεRIα, the α subunit of the human high-affinity Fc receptor for IgE. The receptor is composed of one α-, one β-, and two disulphide-linked γ-chains, of which the α subunit binds IgE1. FcεRIα is expressed on mast and basophil cells, is upregulated in the presence of IgE, and is found on a subset of blood dendritic cells. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions.
Additional information: Clone REA758 displays negligible binding to Fc receptors.

Alternative names

FCER1A, Fce1a, FcERI

Technical specifications

  • Antigen: FcεRIα
  • Clone: REA758
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: FCER1A, Fce1a, FcERI
  • Entrez Gene ID: 2205
  • Molecular mass of antigen [kDa]: 27
  • Distribution of antigen: mast cells, basophils
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1
100 µg in 100 µL