Clone:
REA651
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
TCR Vb10, Gm17526

Specifications for TCR Vβ10 Antibody, anti-mouse, REAfinity™

Overview

Clone REA651 recognizes the mouse V beta 10 T cell receptor (TCR Vβ10). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ10 is a variant of the TCR β chain and is expressed on T cells having the a haplotype, but not with the b and c haplotype of the TCRβ gene complex.
Additional information: Clone REA651 displays negligible binding to Fc receptors.

Alternative names

TCR Vb10, Gm17526

Detailed product information

Technical specifications

CloneREA651
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenTCR Vβ10
Alternative names of antigenTCR Vb10, Gm17526
Distribution of antigenT cells
Entrez Gene ID100124670
RRIDAB_2653731, AB_2653732, AB_2653733, AB_2653734, AB_2653735, AB_2653736, AB_2653737, AB_2653730

Resources for TCR Vβ10 Antibody, anti-mouse, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for TCR Vβ10 Antibody, anti-mouse, REAfinity™

Publications

  1. Bour, H. et al. (1999)
    Dramatic influence of V beta gene polymorphism on an antigen-specific CD8
    +
    T cell response
    in vivo
    .
    J. Immunol. 162(8): 4647-4656
  2. Brenden, N. et al. (1999) Differential MHC expression requirements for positive selection of separate TCR Vb families. Immunogenetics 49(1): 1-6
  3. Deepe, G. S. Jr et al. (2002)
    Discordance between T-cell receptor expression and effector function in mice infected with
    Histoplasma capsulatum
    .
    Infect. Immun. 70(3): 1648-1652

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