CD64 antibodies, human

CD64 antibodies, human

Clone: 10.1.1 | Dilution: 1:11
Clone 10.1.1 reacts with human CD64, a high affinity Fc receptor for IgG. CD64 contains three Ig-like domains in its extracellular domain and binds both monomeric and aggregated IgG and contributes to antibody-dependent cellular cytotoxicity (ADCC), phagocytosis, and the clearance of immune complexes. It is constitutively expressed on macrophages, monocytes, and eosinophils and can be up-regulated on neutrophils during infection or after stimulation with IFN-γ and colony-stimulating factors G-CSF and GM-CSF.

Alternative names

FCGR1A, CD64A, FcR I, IGFR1, FcγRI

Technical specifications

  • Antigen: CD64
  • Clone: 10.1.1
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: FCGR1A, CD64A, FcR I, IGFR1, FcγRI
  • Entrez Gene ID: 2209
  • Molecular mass of antigen [kDa]: 41
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    , baboon, capuchin monkey,
    squirrel monkey (
    Saimiri sciureus
    )
  • Distribution of antigen: dendritic cells, eosinophils, macrophages, monocytes, myeloid cells, neutrophils
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, VioBlue, VioGreen, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin, FITC
  • Selected references

    1. Shen, L. et al. (1987) Polymorphonuclear leukocyte function triggered through the high affinity Fc receptor for monomeric IgG. J. Immunol. 139(2): 534-538
    2. Herra, C. et al. (1996) Increased expression of Fc gamma receptors on neutrophils and monocytes may reflect ongoing bacterial infection. J. Med. Microbiol. 44(2): 135-140
    3. Buckle, A. M. and Hogg, N. (1989) The effect of IFN-gamma and colony-stimulating factors on the expression of neutrophil cell membrane receptors. J. Immunol. 143(7): 2295-2301
Product options: 14
130-097-069

CD64-FITC, human

for 100
tests
(1)
EUR 170,00 
130-100-415

CD64-PE, human

for 30
tests
(1)
EUR 82,00 
130-097-071

CD64-PE, human

for 100
tests
(1)
EUR 201,00 
for 30
tests
(1)
EUR 113,00 
for 100
tests
(1)
EUR 273,00 
for 30
tests
EUR 113,00 
for 100
tests
EUR 273,00 
for 30
tests
(1)
EUR 118,00 
for 100
tests
(1)
EUR 283,00 
for 30
tests
(1)
EUR 118,00 
for 100
tests
(1)
EUR 283,00 
for 30
tests
(1)
EUR 118,00 
for 100
tests
(1)
EUR 283,00 
for 100
tests
(1)
EUR 170,00 

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