Clone:
REAL591
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
gamma-cytoplasmic actin, γ-actin 1, actin gamma 1, ACTG1

Specifications for γ-Actin 1 Antibody, anti-human, REAdye_lease™

Overview

Clone REAL591 is an antibody fragment derived from the full Anti-γ-Actin 1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL591 recognizes the human gamma actin 1 protein, also known as gamma-cytoplasmic actin, encoded by the ACTG1 gene, and belongs to the actin family which consists of highly conserved proteins. Actin gamma 1 is involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.Genomic mutations of ACTG1 lead to DFNA26, Non-syndromic neurosensory deafness autosomal dominant type 20 or Baraitser-Winter syndrome 2 (BRWS2).
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

gamma-cytoplasmic actin, γ-actin 1, actin gamma 1, ACTG1

Detailed product information

Technical specifications

CloneREAL591
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
Cross-reactivitymouse, rat
Antigenγ-Actin 1
Alternative names of antigengamma-cytoplasmic actin, γ-actin 1, actin gamma 1, ACTG1
Distribution of antigencolon

Resources for γ-Actin 1 Antibody, anti-human, REAdye_lease™

Certificates

Please follow this
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References for γ-Actin 1 Antibody, anti-human, REAdye_lease™

Publications

  1. Ostler, N. et al. (2014) Gamma interferon-induced guanylate binding protein 1 is a novel actin cytoskeleton remodeling factor. Mol. Cell. Biol. 34(2): 196-209
  2. Dong, X. et al. (2018) Actin Gamma 1, a new skin cancer pathogenic gene, identified by the biological feature-based classification. J. Cell. Biochem. 119(2): 1406-1419

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