Clone:
REA923
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
Ephrin type-B receptor 4, Hepatoma transmembrane kinase, Tyrosine-protein kinase TYRO11, HTK, MYK1, TYRO11

Specifications for EPHB4 Antibody, anti-human, REAfinity™

Overview

Clone REA923 recognizes the human ephrin type-B receptor 4 (EPHB4) antigen, which is a member of the Eph receptor tyrosine kinase family. The ligand for EPHB4 is ephrin-B2. EPHB4 is found in different tissues, e.g., in placenta, kidney, liver, lung, pancreas, skeletal muscle, and heart. It is expressed on myeloid hematopoietic cells and endothelial cells. EPHB4 functions as an inhibitor for cell-cell adhesion, chemotaxis, and angiogenesis as well as a promoter for the differentiation of megakaryocytic and erythroid progenitor cells.
Additional information: Clone REA923 displays negligible binding to Fc receptors.

Alternative names

Ephrin type-B receptor 4, Hepatoma transmembrane kinase, Tyrosine-protein kinase TYRO11, HTK, MYK1, TYRO11

Detailed product information

Technical specifications

CloneREA923
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenEPHB4
Alternative names of antigenEphrin type-B receptor 4, Hepatoma transmembrane kinase, Tyrosine-protein kinase TYRO11, HTK, MYK1, TYRO11
Molecular mass of antigen [kDa]107
Distribution of antigenendothelial cells, other, breast, colon, kidney, liver, lung, pancreas, placenta, skeletal muscle
Entrez Gene ID2050
RRIDAB_2727059, AB_2727110, AB_2727060, AB_2727111, AB_2727061, AB_2727255, AB_2727213, AB_2727112, AB_2727062, AB_2727113, AB_2727063, AB_2727108, AB_2727058, AB_2727109

Resources for EPHB4 Antibody, anti-human, REAfinity™

Certificates

Please follow this
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References for EPHB4 Antibody, anti-human, REAfinity™

Publications

  1. Erber, R. et al. (2006) EphB4 controls blood vascular morphogenesis during postnatal angiogenesis. EMBO J. 25(3): 628-641
  2. Füller, T. et al. (2003) Forward EphB4 signaling in endothelial cells controls cellular repulsion and segregation from ephrinB2 positive cells. J. Cell. Sci. 116(12): 2461-2470

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