Clone:
Cy34.1
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC, MICS, IF, IHC
Alternative names:
Lyb-8, BL-CAM, SIGLEC-2

Specifications for CD22 Antibody, anti-mouse

Overview

The monoclonal antibody Cy34.1 recognizes the 150 kDa B cell–restricted glycoprotein CD22 on mice strains having the Lyb-8.2 alloantigen, e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR. Lyb-8.2 is expressed at mature levels on all B cell subsets. In bone marrow, CD22 is not detectable on pro–B cells, pre–B cells, and emerging IgM
+
B cells. CD22 plays a strong role in cell interactions and B cell activation.

Alternative names

Lyb-8, BL-CAM, SIGLEC-2

Detailed product information

Technical specifications

CloneCy34.1
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Speciesmouse
AntigenCD22
Alternative names of antigenLyb-8, BL-CAM, SIGLEC-2
Molecular mass of antigen [kDa]94
Distribution of antigenB cells, dendritic cells, basophils
Entrez Gene ID12483
RRIDAB_2656371, AB_2656372, AB_2656373, AB_2656376, AB_2802043

Resources for CD22 Antibody, anti-mouse

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD22 Antibody, anti-mouse

Publications

  1. Erickson, L. D. et al. (1996) Differential expression of CD22 (Lyb8) on murine B cells. Immunogenetics 8(7): 1121-1129
  2. Symington, F. W. et al. (1982) Lyb-8.2: A new B cell antigen defined and characterized with a monoclonal antibody. Immunogenetics 16(5): 381-391
  3. Law, C. L. et al. (1994) Regulation of lymphocyte activation by the cell-surface molecule CD22. Immunol. Today 15(9): 442-449

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CD22 Antibody, anti-mouse

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