Clone:
REAL653
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
LAMP-1, LAMPA, LGP120, LAMP1

Specifications for CD107a (LAMP-1) Antibody, anti-human, REAdye_lease™

Overview

Clone REAL653 is an antibody fragment derived from the full CD107a (LAMP-1) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL565 recognizes the CD107a antigen, also known as lysosome-associated membrane protein 1 (LAMP-1), a 110–140 kDa type I membrane glycoprotein. It is a widely expressed intracellular protein, located in the lysosomal/endosomal membrane. CD107a transiently located on the plasma membrane can be used as a marker for CD8+ T cell degranulation following stimulation. It is also expressed to a lower extent on activated NK cells.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

LAMP-1, LAMPA, LGP120, LAMP1

Detailed product information

Technical specifications

CloneREAL653
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenCD107a (LAMP-1)
Alternative names of antigenLAMP-1, LAMPA, LGP120, LAMP1
Distribution of antigendendritic cells, endothelial cells, epithelial cells, granulocytes, macrophages, platelets, T cells, neutrophils, kidney

Resources for CD107a (LAMP-1) Antibody, anti-human, REAdye_lease™

Certificates

Please follow this
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to search for Certificates of Analysis (CoA) by lot number.

References for CD107a (LAMP-1) Antibody, anti-human, REAdye_lease™

Publications

  1. Sarafian, V.S. et al. (2018) Purification and characterization of human lysosomal membrane glycoproteins. APMIS 268(1): 657-662
  2. Betts, M. R. et al. (2003)
    Sensitive and viable identification of antigen-specific CD8
    +
    T cells by a flow cytometric assay for degranulation.
    J. Immunol. Methods 281: 65-78
  3. Mane, S. M. et al. (1989) Purification and characterization of human lysosomal membrane glycoproteins. Arch Biochem Biophys. 268(1): 360-378

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