Clone:
REA647
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
TCR Vbeta17a, Gm16779, Tcrb-V9

Specifications for TCR Vβ17a Antibody, anti-mouse, REAfinity™

Overview

Clone REA647 recognizes the mouse V beta 17a T cell receptor (TCR Vβ17a). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ17a is a variant of the TCR β chain and is expressed on T cells having the a haplotype (eg. C57L, SJL, SWR) of the TCRβ gene complex.
Additional information: Clone REA647 displays negligible binding to Fc receptors.

Alternative names

TCR Vbeta17a, Gm16779, Tcrb-V9

Detailed product information

Technical specifications

CloneREA647
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenTCR Vβ17a
Alternative names of antigenTCR Vbeta17a, Gm16779, Tcrb-V9
Distribution of antigenT cells
Entrez Gene ID100124681
RRIDAB_2653821, AB_2653822, AB_2653823, AB_2653820

Resources for TCR Vβ17a Antibody, anti-mouse, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for TCR Vβ17a Antibody, anti-mouse, REAfinity™

Publications

  1. Kuchroo, V. K. et al. (1992) Experimental allergic encephalomyelitis mediated by cloned T cells specific for a synthetic peptide of myelin proteolipid protein. Fine specificity and T cell receptor V beta usage. J. Immunol. 148(12): 3776-3782
  2. McDuffie, M. et al. (1992)
    I-E-independent deletion of V beta 17a
    +
    T cells by Mtv-3 from the nonobese diabetic mouse.
    J. Immunol. 148(7): 2097-9102
  3. Katz, J. et al. (1994)
    Expression of superantigen-like specificities on murine sjl/j-B lymphomas - antitumor v-Beta-17a
    +
    T-lymphocytes use a diverse set of T-cell receptor v-alpha-chain gene-sequences.
    Int. J. Oncol. 4(4): 839-847

Related products for
TCR Vβ17a Antibody, anti-mouse, REAfinity™

2 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?