Clone:
REA703
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
Receptor activity-modifying protein 2, CRLR activity-modifying protein 2

Specifications for RAMP2 Antibody, anti-mouse, REAfinity™

Overview

Clone REA703 recognizes the mouse RAMP2 antigen, a 20 kDa single-transmembrane-domain protein expressed in lung, breast, immune system, and fetal tissues. In interaction with the calcitonin receptor-like receptor (CRLR), a class B G protein–coupled receptor (GPCR), RAMP2 forms a heterodimer for adrenomedullin (AM).
Additional information: Clone REA703 displays negligible binding to Fc receptors.

Alternative names

Receptor activity-modifying protein 2, CRLR activity-modifying protein 2

Detailed product information

Technical specifications

CloneREA703
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenRAMP2
Alternative names of antigenReceptor activity-modifying protein 2, CRLR activity-modifying protein 2
Molecular mass of antigen [kDa]17
Distribution of antigenother, breast, lung
Entrez Gene ID54409
RRIDAB_2653342, AB_2653343, AB_2653344, AB_2653345, AB_2653346, AB_2653341

Resources for RAMP2 Antibody, anti-mouse, REAfinity™

Certificates

Please follow this
link
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References for RAMP2 Antibody, anti-mouse, REAfinity™

Publications

  1. McLatchie, L. M. et al. (1998) RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature 393(6683): 333-339
  2. Kusano S. et al. (2012) Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding. Protein Sci. 21(2): 199-210

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