CD58 (LFA-3) antibodies, human

CD58 (LFA-3) antibodies, human

Clone: REA1098 | Dilution: 1:50
Clone REA1098 recognizes human CD58, a 45–70 kDa cell surface molecule which is a member of the immunoglobin superfamily. It is expressed on professional APCs (antigen-presenting cells) such as B cells, dendritic cells, macrophages, and epithelial cells as well as on T cells, monocytes, erythrocytes, endothelial cells, and fibroblasts. LFA-3 interacts with CD2 on T cells and is important for interaction between T cells and professional APCs.
Additional information: Clone REA1098 displays negligible binding to Fc receptors.

Alternative names

LFA-3, ag3

Technical specifications

  • Antigen: CD58 (LFA-3)
  • Clone: REA1098
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: LFA-3, ag3
  • Entrez Gene ID: 965
  • Molecular mass of antigen [kDa]: 25
  • Distribution of antigen: B cells, dendritic cells, endothelial cells, epithelial cells, fibroblasts, macrophages, monocytes, T cells, red blood cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio615, VioBright 515
  • Selected references

    1. Sanchez-Madrid, F. et al. (1982) Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U.S.A. 79: 7489-7493
    2. Dengler, T. J. et al. (1992) Structural and functional epitopes of the human adhesion receptor CD58 (LFA-3). Eur. J. Immunol. 22(11): 2809-2817
    3. Wang, J. H. et al. (1999) Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors. Cell 97(6): 791-803
Product options: 8
for 30
tests
(1)
EUR 115,00 
for 100
tests
(1)
EUR 285,00 
for 30
tests
(1)
EUR 115,00 
for 100
tests
(1)
EUR 285,00 
for 30
tests
(1)
EUR 130,00 
for 100
tests
(1)
EUR 310,00 
for 30
tests
(1)
EUR 165,00 
for 100
tests
(1)
EUR 390,00