CD4 antibodies, mouse

CD4 antibodies, mouse

Clone: REA1211 | Dilution: 1:50
Clone REA1211 recognizes the mouse CD4 antigen, a cell surface glycoprotein, which is a member of the immunoglobulin superfamily. It is also known as L3T4 or Leu-3. In mice, CD4 is expressed on T helper cells, regulatory T cells, and at lower levels on subpopulations of NKT cells and dendritic cells. It is furthermore detected on most thymocytes (CD4
+
CD8
+
and CD4
+
CD8
thymocytes). CD4 interacts with MHC class II molecules on the surface of antigen presenting cells. It increases the avidity of the interaction between T cells and antigen-presenting or target cells.
Additional information: Clone REA1211 displays negligible binding to Fc receptors.

Alternative names

L3T4, T4, Leu-3, Ly-4

Technical specifications

  • Antigen: CD4
  • Clone: REA1211
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: L3T4, T4, Leu-3, Ly-4
  • Entrez Gene ID: 12504
  • Molecular mass of antigen [kDa]: 48
  • Distribution of antigen: T cells, dendritic cells, NKT cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin, PE
  • Selected references

    1. Tourvieille, B. et al. (1986) Isolation and sequence of L3T4 complementary DNA clones: expression in T cells and brain. Science 234(4776): 610-614
    2. Bierer, B. E. et al. (1989) The biologic roles of CD2, CD4, and CD8 in T-cell activation. Annu. Rev. Immunol. 7: 579-599
    3. Parnes, J. R. et al. (1987) L3T4 and the immunoglobulin gene superfamily: new relationships between the immune system and the nervous system. Immunol. Rev. 100: 109-127
Product options: 10
130-123-206

CD4-PE, mouse

30 µg in 200 µL (1)
EUR 65,00 
130-123-207

CD4-APC, mouse

30 µg in 200 µL (1)
EUR 65,00 
30 µg in 200 µL (1)
EUR 105,00 
30 µg in 200 µL (1)
EUR 105,00 
30 µg in 200 µL (1)
EUR 110,00 
30 µg in 200 µL (1)
EUR 110,00 
30 µg in 200 µL (1)
EUR 110,00 
30 µg in 200 µL (1)
EUR 110,00 
30 µg in 200 µL (1)
EUR 155,00 
30 µg in 200 µL (1)
EUR 40,00