CD298 antibodies, human

CD298 antibodies, human

Clone: REA217 | Dilution: 1:50
Clone REA217 recognizes CD298, the β3 subunit isoform of Na
+
, K
+
-ATPase, which is a membrane associated enzyme. Na
+
, K
+
-ATPase transports Na
+
and K
+
by coupling the hydrolysis of ATP to the transport of Na
+
and K
+
. The movement of ions across the plasma membrane generates and maintains the electrochemical gradient required for osmoregulation, transport of molecules and nutrients. Na
+
, K
+
-ATPase consists of large catalytic α subunit and a smaller glycoprotein non-catalytic β subunit, which exists in three known isoforms.
Additional information: Clone REA217 displays negligible binding to Fc receptors.

Alternative names

ATP1B3, ATPB-3

Technical specifications

  • Antigen: CD298
  • Clone: REA217
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: ATP1B3, ATPB-3
  • Distribution of antigen: leukocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC
  • Selected references

    1. Jørgensen, P. L. et al. (1982)
      Mechanism of the Na
      +
      , K
      +
      pump. Protein structure and conformations of the pure (Na
      +
      , K
      +
      )-ATPase.
      Biochim. Biophys. Acta 694(1): 27-68
    2. Malik, N. et al. (1996) Identification of the mammalian Na,K-ATPase 3 subunit. J. Biol. Chem. 271(37): 22754-22758
    3. Chiampanichayakul, S. et al. (2006) Na, K ATPase beta3 subunit (CD298): association with alpha subunit and expression on peripheral blood cells. Tissue Antigens 68(6): 517-509
Product options: 2
for 30
tests
(1)
EUR 105,00 
for 100
tests
(1)
EUR 245,00 

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