Anti-IL-5 antibodies, mouse

Anti-IL-5 antibodies, mouse

Clone: REA1009 | Dilution: 1:50
Clone REA1009 recognizes the mouse interleukin-5 (IL-5), which is is predominantly secreted by CD4
+
T cells. It promotes growth and activation of eosinophils. Furthermore, it is involved in a range of allergic reactions and mediates immune reactions against parasites. IL-5 also acts on other cell types such as B cells.
Additional information: Clone REA1009 displays negligible binding to Fc receptors.

Alternative names

IL5, B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor, TRF

Technical specifications

  • Antigen: IL-5
  • Clone: REA1009
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: IL5, B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor, TRF
  • Entrez Gene ID: 16191
  • Molecular mass of antigen [kDa]: 13
  • Cross-reactivity: human
  • Distribution of antigen: T cells, T helper cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC
  • Selected references

    1. Schwarze, J. et al. (1999) IL-5 and eosinophils are essential for the development of airway hyperresponsiveness following acute respiratory syncytial virus infection. J. Immunol. 162(5): 2997-3004
    2. Brunet, L. R. et al. (1999)
      Interleukin 5 (IL-5) is not required for expression of a Tʜ2 response or host resistance mechanisms during murine
      schistosomiasis mansoni
      but does play a role in development of IL-4-producing non-T, non-B cells.
      Infect. Immun. 67(6): 3014-3018
Product options: 4
30 µg in 200 µL (1)
EUR 85,00 
150 µg in 1 mL (1)
EUR 285,00 
30 µg in 200 µL (1)
EUR 85,00 
150 µg in 1 mL (1)
EUR 285,00 

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