Anti-HLA-A3, human

Anti-HLA-A3, human

Clone: REA950 | Dilution: 1:50
Clone REA950 recognizes the human major histocompatibility complex (MHC) class I molecule HLA-A3, a heterodimer belonging to the HLA-A family and consisting of two subtypes, A3.1 and A3.2. HLA-A has a heavy chain (anchored in the membrane) and a light chain (beta-2 microglobulin). MHC class I molecules are expressed on nearly all nucleated cells and present small intracellular peptides on the cell surface to the immune system. The peptids are recognized by circulating CD8
+
cytotoxic T lymphocytes.
Additional information: Clone REA950 displays negligible binding to Fc receptors.

Alternative names

HLAA

Technical specifications

  • Antigen: HLA-A3
  • Clone: REA950
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: HLAA
  • Entrez Gene ID: 3105
  • Molecular mass of antigen [kDa]: 38
  • Distribution of antigen: ubiquitous
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio615, PE-Vio770, APC-Vio770
  • Selected references

    1. Jelachich, M. L. et al. (1988) Analysis of the molecular basis of HLA-A3 recognition by cytotoxic T cells using defined mutants of the HLA-A3 molecule. J. Immunol. 141(4): 1108-1113
    2. Vonderheide, R. H. et al. (2001) Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase. Clin. Cancer Res. 7(11): 3343-3348
Product options: 12
for 30
tests
(1)
EUR 100,00 
for 100
tests
(1)
EUR 240,00 
for 30
tests
(1)
EUR 115,00 
for 100
tests
(1)
EUR 285,00 
for 30
tests
(1)
EUR 115,00 
for 100
tests
(1)
EUR 285,00 
for 30
tests
(1)
EUR 130,00 
for 100
tests
(1)
EUR 310,00 
for 30
tests
(1)
EUR 130,00 
for 100
tests
(1)
EUR 310,00 
for 30
tests
(1)
EUR 130,00 
for 100
tests
(1)
EUR 310,00 

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