Clone:
REA873
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC

Specifications for CXCL16 Antibody, anti-human, REAfinity™

Overview

Clone REA873 recognizes the human CXCL16 cytokine belonging to the CXC chemokine family. It consists of a transmembrane region and a chemokine domain suspended by a mucin-like stalk. CXCL16 is secreted by dendritc cells localized in the T cell zones of lymphoid organs, and by cells found in the red pulp of the spleen. The expression of CXCL16 is induced by the inflammatory cytokines IFN-γ and TNF-α. The receptor of CXCL16 is CD186, also known as CXCR6, Bonzo, or STRL33, which is activated by CXCL16, which leads to chemotaxis of T cells.
Additional information: Clone REA873 displays negligible binding to Fc receptors.

Detailed product information

Technical specifications

CloneREA873
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCXCL16
Molecular mass of antigen [kDa]24
Distribution of antigenT cells, dendritic cells
Entrez Gene ID58191
RRIDAB_2726573, AB_2726503, AB_2726574, AB_2726504, AB_2726572, AB_2726502

Resources for CXCL16 Antibody, anti-human, REAfinity™

Certificates

Please follow this
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to search for Certificates of Analysis (CoA) by lot number.

References for CXCL16 Antibody, anti-human, REAfinity™

Publications

  1. Matloubian, M. et al. (2000) A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. Nat. Immunol. 1(4): 298-304
  2. Wilbanks, A. et al. (2001) Expression cloning of the STRL33/BONZO/TYMSTRligand reveals elements of CC, CXC, and CX3C chemokines. J. Immunol. 166(8): 5145-5154
  3. Abel, S. et al. (2004) The CCL7-CCL2-CCR2 axis regulates IL-4 production in lungs and fungal immunity. J. Immunol. 172(10): 6362-6372

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