Clone:
REA1158
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IF, IHC
Alternative names:
CEA, Carcinoembryonic antigen

Specifications for CD66 (CEA) Antibody, anti-human, REAfinity™

Overview

Clone REA1158 recognizes the human CD66 antigen, also known as CEA (Carcinoembryonic antigen), a cell-surface-anchored glycoprotein, which is a member of the Ig superfamily. CEA plays a role in in cell adhesion and contributes to tumorigenicity by inhibiting cellular differentiation. CEA is used as an important tumor marker for colorectal and other carcinomas.
Additional information: Clone REA1158 displays negligible binding to Fc receptors.

Alternative names

CEA, Carcinoembryonic antigen

Detailed product information

Technical specifications

CloneREA1158
Clonalitymonoclonal
Isotyperecombinant human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD66 (CEA)
Alternative names of antigenCEA, Carcinoembryonic antigen
RRIDAB_2857524, AB_2857523

Resources for CD66 (CEA) Antibody, anti-human, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD66 (CEA) Antibody, anti-human, REAfinity™

Publications

  1. Hammarström, S. (1999) The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. Semin. Cancer Biol. 9(2): 67-81
  2. Boehm, M.K. et al. (2000) Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23. FEBS Lett. 475(1): 11-16
  3. Taheri, M. et al. (2000) Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion. J. Biol. Chem. 275(35): 26935-26943

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