Clone:
REA1106
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC, MC
Alternative names:
Itga1, VLA-1

Specifications for CD49a Antibody, anti-human, REAfinity™

Overview

Clone REA1106 recognizes the cell adhesion molecule human CD49a, which is a 200 kDa heterodimeric integrin receptor. CD49a, also known as integrin α1, interacts with integrin β1 (CD29) to form the VLA-1 complex which functions as a receptor for collagen and laminin-1. Integrin α1 plays a role in cell-cell adhesion and T cell proliferation and is expressed by activated T cells, NK cells, neuronal cells, fibroblasts, and mesenchymal cells.
Additional information: Clone REA1106 displays negligible binding to Fc receptors.

Alternative names

Itga1, VLA-1

Detailed product information

Technical specifications

CloneREA1106
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD49a
Alternative names of antigenItga1, VLA-1
Molecular mass of antigen [kDa]128
Distribution of antigenfibroblasts, neurons, NK cells, T cells, mesenchymal stem cells
Entrez Gene ID3672
RRIDAB_2733648, AB_2733820, AB_2733821, AB_2733384, AB_2733385, AB_2732980, AB_2732981, AB_2733240, AB_2733241, AB_2733133, AB_2733134, AB_2734023, AB_2734024, AB_2733528, AB_2733529, AB_2733647

Resources for CD49a Antibody, anti-human, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD49a Antibody, anti-human, REAfinity™

Publications

  1. Hemler, M. E. et al. (1985) Biochemical characterization of VLA-1 and VLA-2. Cell surface heterodimers on activated T cells. J. Biol. Chem. 260: 15246-15252
  2. Miettinen, M. et al. (1993) Distribution of VLA integrins in solid tumors. Emergence of tumor-type-related expression. Patterns in carcinomas and sarcomas. Am. J. Pathol. 142(4): 1009-1018
  3. Boiret, N. et al. (2005) Characterization of nonexpanded mesenchymal progenitor cells from normal adult human bone marrow. Exp. Hematol. 33(2): 219-225

Related products for
CD49a Antibody, anti-human, REAfinity™

3 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?