Clone:
8C11
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC
Alternative names:
Cadherin-2, CDw325, Neural cadherin, N-cadherin

Specifications for CD325 (N-Cadherin) Antibody, anti-human/mouse

Overview

Clone 8C11 recognizes the human and mouse CD325, also known as cadherin-2 or N-cadherin. CD325, an integral adhesion glycoprotein, consists of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CD325 is a member of cadherins, which are involved in cell adhesion, forming adherens junctions. This is mediated by the extracellular domains of cadherins, whereas the intracellular cytoplasmic tail associates with different adaptor and signaling proteins. The activity of CD325 depends on protein-protein interactions and phosphorylation/dephosphorylation actions.

Alternative names

Cadherin-2, CDw325, Neural cadherin, N-cadherin

Detailed product information

Technical specifications

Clone8C11
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman, mouse
AntigenCD325 (N-Cadherin)
Alternative names of antigenCadherin-2, CDw325, Neural cadherin, N-cadherin
Molecular mass of antigen [kDa]82
Distribution of antigenendothelial cells, other
Entrez Gene ID1000, 12558
RRIDAB_2727443, AB_2727380, AB_2727444, AB_2727381

Resources for CD325 (N-Cadherin) Antibody, anti-human/mouse

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD325 (N-Cadherin) Antibody, anti-human/mouse

Publications

  1. Salomon, D. et al. (1992) Extrajunctional distribution of N-cadherin in cultured human endothelial cells. J. Cell. Sci. 102: 7-17
  2. Puch, S. et al. (2001) N-cadherin is developmentally regulated and functionally involved in early hematopoietic cell differentiation. J. Cell. Sci. 114(8): 1567-1577

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