Clone:
REA1116
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
KDR, Flk-1, Flk1, Krd-1, Ly73, VEGFR2, sVEGFR-2

Specifications for CD309 (VEGFR-2) Antibody, anti-mouse, REAfinity™

Overview

Clone REA1116 recognizes CD309, a receptor tyrosine kinase of the class 3 subfamily also known as vascular endothelial growth factor receptor 2 (VEGFR2), kinase insert domain receptor (KDR), or fetal liver kinase-1 (Flk-1). CD309 plays an important role in angiogenesis, vascular and endothelial processes, as well as in embryonic hematopoiesis and promotes reorganization of the actin cytoskeleton. CD309 (VEGFR-2) is expressed on embryonic and adult endothelial cells and endothelial progenitor cells.
Additional information: Clone REA1116 displays negligible binding to Fc receptors.

Alternative names

KDR, Flk-1, Flk1, Krd-1, Ly73, VEGFR2, sVEGFR-2

Detailed product information

Technical specifications

CloneREA1116
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD309 (VEGFR-2)
Alternative names of antigenKDR, Flk-1, Flk1, Krd-1, Ly73, VEGFR2, sVEGFR-2
Molecular mass of antigen [kDa]150
Distribution of antigenendothelial cells, megakaryocytes, platelets, ES and iPS cells, pancreas, smooth muscle
Entrez Gene ID16542
RRIDAB_2733730, AB_2733731, AB_2733309, AB_2732937, AB_2733183, AB_2733087, AB_2733986, AB_2733987, AB_2733478, AB_2733598

Resources for CD309 (VEGFR-2) Antibody, anti-mouse, REAfinity™

Certificates

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References for CD309 (VEGFR-2) Antibody, anti-mouse, REAfinity™

Publications

  1. Kataoka, H. et al. (1997) Expressions of PDGF receptor alpha, c-Kit and Flk1 genes clustering in mouse chromosome 5 define distinct subsets of nascent mesodermal cells. Dev. Growth Differ. 39(6): 729-740
  2. Ferrara, N. et al. (2003) The biology of VEGF and its receptors. Nat Med 9: 669-676

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