Clone:
UP-D2
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC
Alternative names:
CD300LF, CLM-1, IREM-1, IgSF13, LMIR3, NKIR, CLM

Specifications for CD300f (IREM-1) Antibody, anti-human

Overview

The monoclonal antibody UP-D2 reacts with human CD300f, also known as immune receptor expressed by myeloid cell 1 (IREM-1) which is a type I transmembrane glycoprotein member of the CD300 family. It is expressed on myeloid cells and in peripheral blood on monocytes and granulocytes. IREM-1 binds the p85α regulatory subunit of phosphoinositide 3-kinase (PI3K) and can enhance phagocytosis of apoptotic cells.

Alternative names

CD300LF, CLM-1, IREM-1, IgSF13, LMIR3, NKIR, CLM

Detailed product information

Technical specifications

CloneUP-D2
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD300f (IREM-1)
Alternative names of antigenCD300LF, CLM-1, IREM-1, IgSF13, LMIR3, NKIR, CLM
Molecular mass of antigen [kDa]30
Distribution of antigenmyeloid cells, granulocytes, monocytes
Entrez Gene ID146722
RRIDAB_2751484, AB_2657154, AB_2657156, AB_2657157, AB_2657158, AB_2751521

Resources for CD300f (IREM-1) Antibody, anti-human

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD300f (IREM-1) Antibody, anti-human

Publications

  1. Álvarez-Errico, D. et al. (2007) The IREM-1 (CD300f) inhibitory receptor associates with the p85α subunit of phosphoinositide 3-kinase. J. Immunol. 178: 808-816
  2. Choi, S. C. et al. (2011) Cutting edge: mouse CD300f (CMRF-35-like molecule-1) recognizes outer membrane-exposed phosphatidylserine and can promote phagocytosis. J. Immunol. 187(7): 3483-3487
  3. Álvarez-Errico, D. et al. (2004) IREM-1 is a novel inhibitory receptor expressed by myeloid cells. Eur. J. Immunol. 34(12): 3690-3701

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